Toxicology of Glutathione Transferases

The most important enzymes protecting human and other organisms from potentially toxic chemicals, Glutathione S-transferases (GSTs) are central to basic mechanisms such as stress response and physiological functions including protection against lipid peroxidation. This book describes the role of GST in toxicology, focusing on their pharmacologic and physiological roles and their relevance to biological toxicology. It covers structure and function, gene regulation, and these enzymes’ involvement in signal transduction. Reflecting current trends in this expanding research area, Toxicology of Glutathione Transferases is the only source that details the methods of GST research.