Drug Discovery

Marine plants are potential sources of nutrients and are also valuable for developing new drugs due to their unique bioactive compounds. This is the first book of its kind written by scientists from both the Marine Biology and Pharmacy disciplines to fill the long-felt need for a marine natural prod..

This text traces developments in rational drug discovery and combinatorial library design with contributions from 50 leading scientists in academia and industry who offer coverage of basic principles, design strategies, methodologies, software tools and algorithms, and applications. It outlines the ..

There is a compelling need for new drugs and efficient treatments against mosquito-borne diseases. Computational Design of Chemicals for the Control of Mosquitoes and Their Diseases explains how the search for new substances effective against mosquitoes and their diseases has benefited from the use ..

With more than half of drug targets based on GPCRs, there is great interest in finding high-resolution structures for recombinantly expressed GPCRs, discovering novel drug interactions, and designing structure-based drug therapies that display improved efficacy and selectivity with lesser side effec..

This timely, expanded new edition is the definitive handbook for experienced drug metabolism and pharmaceutical scientists and those new to the field._x005F_x000D_ _x005F_x000D_ Written by internationally renowned authors, it provides integrated, comprehensive coverage of fundamental aspects of drug..

Imaging technologies are receiving much attention in the pharmaceutical industry because of their potential for accelerating drug discovery and development. Magnetic Resonance Imaging (MRI) is one of the principal imaging modalities because it allows information to be gathered non-invasively. The n..

Integrated Drug Discovery Technologies provides a global overview of emerging drug development technologies by presenting and integrating new techniques from the disciplines of chemistry, biology, and computational sciences. It combines integration of contemporary mechanization with strategies in dr..

This text offers in-depth perspectives on every aspect of protein structure identification, assessment, characterization, and utilization, providing a clear understanding of the diversity of protein shapes, variations in protein function, and structure-based drug design. The authors cover numerous h..

Clarifying the scope and limitations of virtual screening, this book explores the algorithms involved and how to use them, offering easy access to strategies and techniques for lead discovery. Part I offers perspectives on ligand-based and docking-based virtual screens, framing the challenges facing..